The Lipids

Chapter 5

Quote of the Day: "Every gain made by individuals or society is almost instantly taken for granted." [Aldous Huxley]

Summary -

Chapter Five describes Lipids (Fats and Oils) and introduces phospholipids and sterols. This chapter describes fats in foods and in the body and outlines the potential hazards of high fat diets, such as the involvement of the lipoprotein’s LDL and HDL with heart disease. The chemical structures of saturated and unsaturated fats are revealed, emulsification is explained, digestion, transport and absorption of fats in the body are discussed. How to read labels for fat content is also covered. Finally, fat replacers are mentioned and their use in low calorie diets. Controversy 5 gives some information about fat calories.

After you have completed your study of this chapter, you should have acquired the following knowledge and skills.  You should be able to:

  • Explain the way lipids are useful, both in foods and in the body.
  • Describe the structure of a triglyceride noting the differences between saturated and unsaturated fats.
  • Summarize the processes of lipid digestion, absorption, transport, and utilization in the body, Including the significance of the lipoproteins.
  • Explain why manufacturers frequently hydrogenate fats and the possible health implications of consuming the trans-fatty acids formed during hydrogenation.
  • List the arguments for and against the growing use of the fat replacers Simplesse and olestra.
  • Plan a diet containing fat in the proper proportions and in the recommended amounts to provide optimal health and pleasure in eating.
  • Discuss the possible roles of high-fat diets in the causation of obesity.

 

Introduction (0:39)

Intro

Lipids - a family of chemical compounds, soluble in organic solvents, insoluble in water. 

Triglycerides are the most common lipids (what we call fat) and comprise approximately 95% of dietary fat. Triglycerides are used for energy and stored in the body's fat cells. This energy source has twice the calories of Carbohydrate or Protein.

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Other Lipids - The remainder of dietary fat is found mostly in two other classes of compounds listed below.

phospholipids -structural relatives of triglycerides made by substituting a polar phosphate group for one of the terminal fatty acids in a triglyceride making the structure amphiphilic (or a good emulsifier).

lecithin.jpg (71262 bytes)

sterol - heterocyclic ring compounds that have no relationship to triglyceride structure. These are lipids because of solubility considerations only and include Vitamin D, steroid hormones and bile.  These compounds are necessary for proper health and are derived from cholesterol.  This is an example of the positive role cholesterol plays in our body (and why our bodies synthesize cholesterol).

 

Fats and Oils (3:06)

Fats & Oils

 

Fatty Acids (3:00)

Fatty Acids

 

Solubility (0:27)

Solubility


Flavor (2:31)

Flavor

Melting Point
Fats and oils are made up of mostly triglycerides and are chemically similar. They differ in
fatty acid saturation, which affects melting point. The melting point is the temperature when a substance changes from solid to liquid. Fats are solid at room temperature due to their higher saturated fatty acid content and their melting points are higher than room temperature. Oils are liquid at room temperature due to their higher polyunsaturated fatty acid content and their melting points are lower than room temperature.
Most plant and marine (fish and other sea creatures) life are subject to environmental temperatures that fall well below room temperature. Hence, it is critical to their survival to have oils as their lipid material. If their lipid material were fat that solidified at environmental temperatures, they would die. Plant and marine lipids are high in unsaturated fatty acids and have lower melting points than lipids composed with more saturated fatty acids.

Solubility
Oil and water separate; fat-soluble compounds stay dissolved in the oil and water-soluble compounds stay dissolved in water.  The process of mixing fats with water is called
Emulsification.   Emulsifiers  have a hydrophilic (fatty acid with phosphate group) and hydrophobic (regular fatty acid) ends. Emulsifiers help solubilize hydrophobic molecules. Both phospholipids and bile act as emulsifyers.

Flavor
Many of the flavors we enjoy in food are due to lipid soluble chemicals in fats and oils. It is no surprise that Fats and Oils taste good. So good in fact that many of us eat too much of these!

Much controversy shrouds the truth about fatty acids and health.  We must keep in mind that too much fat is not good for us. High fat diets have been linked to cardiovascular disease, some types of cancer, and other degenerative diseases.

 

Triglycerides book3.gif (1005 bytes) 136

Triglycerides (4:52)

Triglycerides


 

 

 

 

Fatty Acid Composition (5:07)

Fatty Acid
Composition


Where Canola Oil Got Its Name (0:51)

Canola


 

 

 

 

 

 

Animal vs. Plant Sources of Fatty Acids (2:05)

Animal vs
Plant Sources


Fats in the Food Chain (1:33)

Fats in the Food Chain



Fatty Acids and Glycerol combine to form triglycerides. (Fig. 5-3).   Although these dietary fats are catagorized as saturated, monounsaturated or polyunsaturated, there is no such thing as a pure source of these triglycerides in nature.   Triglycerides are naturally composed of a variety of different fatty acid lengths and saturation.  The fats and oils that are considered "polyunsaturated" contain the greatest proportion of polyunsaturated  fatty acids relative to other fatty acids in the product.

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SFA’s Saturated Fatty Acids

sat fatty acid

MUFA’S Monounsaturated Fatty Acids (Fig. 5-4)

mono fatty acid

PUFA’S Polyunsaturated Fatty Acids

poly fatty acid

Essential Fatty Acids (EFA)
EFA’s
are triglycerides with distinct properties and are necessary as building blocks. As mentioned in Chapter 1, some essential fatty acids are needed to build membranes and other cellular structures. While only small amounts are required, EFA's are vital and deficiency symptoms arise when needs are not met. A teaspoon or so of olive or other unsaturated oil each day is more than enough to met the needs of EFA’s.

Below are the two types of Essential Polyunsaturated fatty acids (EFA’s)

Animal and Fish sources vs. Plant sources

Linoleic acid - Omega-6 Family in many vegetable oils

Linolenic acid - Omega-3 Family in many fish oils

Fish oils are thought to be healthful, but it is not recommended that they be used as supplements. Read the section on Fish Oil Supplements on Page 149 of your text.

Other nutrients necessary in the diet are the fat soluble vitamins A, D, E, and K. Foods containing some fat are needed as the medium for the absorption of these vitamins.

 

Fats and Foods (1:20)

Fats in Foods

 

Fats as Storage (3:08)

Fats as
Storage

 

Fats in the Body (0:53)

Fats in Body

Fats in Foods
  • Provide essential fatty acids
  • Provide concentrated food energy
  • Carry fat soluble vitamins
  • Provide raw materials for synthesis
  • Stimulate appetite, provide satiety

Fats in the Body

  • Chief form of stored energy in the body (1 pound of fat = 3500 Kcal)
  • Provide energy to do work
  • Serve as emergency fuel in hard times
  • Fat pads protect organs from shock
  • Insulate against the cold
  • Major component of cell membranes
  • Converted to other compounds on demand

 

Digestion and Absorption of Dietary Fat book3.gif (1005 bytes) 140

Digestion of Fats (5:39)

Digestion


Absorption of Fats (2:38)

Absorption


Lipid Transport (5:16)

Transport

 

 

 

 

 

 

 

 

 

 

 

 

Cholesterol Transport (1:48)

Cholesterol
Transport

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The presence of dietary fat in the stomach will slow down the release of foodstuff from the stomach to the small intestine. Fat digestion begins when the fat reaches the small intestine, mixes with bile, and becomes available to the appropriate enzymes.

Digestion - bile emulsifies (solubilizes) fats so pancreatic lipase enzymes can function to split fatty acids from triglycerides to form glycerol, free fatty acids, di- and monoglycerides.

Free fatty acids, monoglycerides and glycerol form small beads called micelles once emulsified in the intestines, and await being shuttled across the mucous membranes of the intestinal villi.

Absorption – Glycerol, short chain fatty acids, and some medium chain triglycerides can go directly into the circulatory system. Larger products, such as the long chain fatty acids and monoglycerides must be formed into micelles, absorbed into intestinal cells, incorporated into chylomicrons in the intestinal cell, and released into the lymph system. Once in the lymph system, these chylomicrons (a class of lipoprotein) are released into the circulatory system via the thorasic duct.

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Chylomicrons circulate through the body to deliver dietary fat to cells (with great efficiency!) and the liver. The liver assembles lipoproteins made up of triglycerides, cholesterol and proteins to form Low Density Lipoprotein (LDL’s) which deliver fat to cells, and High Density Lipoproteins (HDL’s) which carry fats from cells to the liver

Lipid Transport - HDL’s (good lipoproteins) and LDL’s (bad lipoproteins) exist for the transportation of fatty acids and cholesterol through the circulatory system. These lipoproteins deliver building blocks (LDL) and clear excess materials (HDL) in the maintenance of cell membranes and nervous tissue.

 

Relative Sizes of Lipoproteins

 

Disease Risk (1:11)

Disease Risk

 

Normal Cholesterol Levels (1:05)

Normal Lipid Levels

 

NCEP (3:17)

NCEP

 

Food Cholesterol (0:40)

Food
Cholesterol

 

Raising HDL (1:27)

Raising HDL's

Fats Increase Risks of Disease
The main risk factors for Cardiovascular Disease, or CVD, include smoking, hypertension and high blood cholesterol.

Normal Blood Lipid Levels
Total Cholesterol < 200 mg/dL
Total Triglycerides < 200 mg/dL
LDL < 130 mg/dL
HDL > 35 mg/dL

What does food cholesterol have to do with blood cholesterol?

Food Cholesterol has minor influence on blood cholesterol in most humans!
Blood Cholesterol level is much more related to amount of fat in diet.
See lecture clips in left margin for the National Cholesterol Education Program (NCEP) Recommendations

Fat transport in blood requires cholesterol containing lipoproteins. Reducing dietary fat intake can decrease the need for the body to synthesize cholesterol for dietary fat transport.

  • High levels of LDL in blood is one of the big risk factors for cardiovascular disease.
  • High levels of HDL in blood is associated with a low risk of heart attacks. To raise HDL’s, exercise more, lose weight and stop smoking.

See Table 5 - 2 for recommendations about dietary fat intake.

 

Obesity is often a risk factor associated with disease, and obesity itself is considered a disease.  A person wishing to reduce the amount of stored fat in their body is more likely to be successful when following a moderate weight-loss plan.  One pound of fat is the equivalent of 3500 Calories.  If a person reduced their Calorie intake by 500 each day, that person could loose one pound of fat per week (500 x 7 = 3500).  Some folks fall in the trap of thinking more Calorie restriction is better, which is not true.  Our bodies have an incredible ability to adapt to events and surroundings to ensure effeciency. A rapid and big reduction in Calorie intake will most likely lead to "starvation mode" which initiates many mechanisms including catabolism of visceral protein.  Catabolism of protein is followed by diuresis to eliminate the urea.  The resulting weight loss is mostly lean tissue and water......these are two components that you do not want to loose.
Weight control is covered in more detail in Chapter 9.

 

 

 

Fat Replacers and other inventions book3.gif (1005 bytes) 153
Fat substitutes include Simplesse (a texturizing agent made from egg protein) and olestra (sucrose polyester), and many more.   These products are now permitted in certain foods and serve to reduce the calorie content of snack and desert foods.

WOW® Potato Chips from Frito Lay are the latest low fat product made using olestra.  Most people that try these chips have no digestion problems, however, excessive intake of the chips have led to "anal leakage".  Another complaint about this product is that the mouth "feel" is not the same.

These products try to mimic texture and flavor, but they are not without problems and side effects in some people.

Benecol, a new product approved May 17, 1999 by FDA, is a margarine containing plant stanol ester that has the effect of lowering blood cholesterol levels.  This product was first produced in Finland and has been sold there since 1995.

Xenical is a prescription drug that prevents absorption of nearly a third of fat consumed.  This product was approved April 26, 1999 by FDA, is intended for the clinically obese and not just dieters.

 

 

Hydrogenation (5:00)

Hydro-
genation

Hydrogenation is the adding of hydrogen to unsaturated fatty acids of dietary fats to increase saturation. This process reduces susceptibility to oxidation in polyunsaturated fatty acids, and renders the fatty acids more stable from rancidity.

cis and trans fatty acid double bonds are found in unsaturated fatty acids, but only the cis forms are natural and usable by the body.

Trans fatty acids occur minimally in nature and abundantly in processed foods. Trans fatty acids are the result of hydrogenation and cause an increase in LDL cholesterol and decrease in HDL cholesterol, which increases the risk of heart disease.

Some cis fatty acids are converted to trans during hydrogenation, hence the concern that hydrogenated oils are less healthful than 'natural' oils.

 

Fats in Meats (1:22)

Fats in Meat


 

 

 

 

 

 

You can use information about fat content in foods to help choose a low fat diet.   Since fat is the most energy dense nutrient (9 Kcal/gram), reducing total fat intake can help reduce total Calorie intake and lead to weight reduction. 

Calorie content -
One portion of fat is 5 grams by weight (about one teaspoonful) and contains 45 calories.

Below are portion sizes (not serving sizes)

  • teaspoon oil or shortening
  • 1 1/2 teaspoon mayonnaise, butter or margarine
  • 1 tablespoon regular salad dressing, cream cheese, or heavy cream
  • 1 1/2 tablespoon sour cream

potato

Meats, Poultry, Fish, Dry Beans, Eggs, and Nuts Group - a serving size is 3 oz.

One oz. lean (free of visible fat) meat has 3 g fat [10%]
One oz. medium (some visible fat) meat has 5 g fat [20%]
One oz. High fat (plenty of visible fat) meat has 8 g fat [30%]

pork chop

Milk, Yogurt, and Cheese group -

Cheese is @ 1/3 fat, Standard milk is 3.2% fat, lower fat milks are popular.
Ice Cream, cakes and cookies are high. Candy is very high in saturated fat.

milk

Bread, Cereal, Rice, and Pasta Group -

Cereal products can be low in fat.
Baked goods often have high amounts of hidden fat.
Fried foods (most fast foods) are loaded with extra fat.
Potato chips, popcorn, corn chips, etc. are high in undesirable saturated fat.
Look at a Potato Chip bag Nutrition Facts label. You will find that over 60% of the calories in potato chips come from fat, and most of that will be saturated.

Examine the information in Figure 5-19. This will help you to understand how you can start now to reduce the amount of fat in your diet.

 

fat label

Total fat, saturated fat, cholesterol and calories from fat for a serving of food are required on all food labels. Be careful! Don’t forget to check the serving size, it may be a fraction of what you consider a serving.

The fat components listed on food labels are listed in grams and in % Daily Values. The definition of the %DV is described near the bottom of the label and the gram values for both a 2000 Calorie and 2500 Calorie diet are listed.

See Chapter 2 about reading food labels