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Digestion |

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Absorption |

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Transport |

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Cholesterol
Transport |
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The presence of dietary fat in the
stomach will slow down the release of foodstuff from the stomach to the small intestine. Fat digestion begins
when the fat reaches the small intestine, mixes with bile, and becomes available to the appropriate enzymes.
Digestion - bile emulsifies
(solubilizes) fats so pancreatic lipase enzymes can function to split fatty acids
from triglycerides to form glycerol, free fatty acids, di- and monoglycerides.
Free fatty acids, monoglycerides and
glycerol form small beads called micelles once emulsified in the intestines, and await
being shuttled across the mucous membranes of the intestinal villi.
Absorption Glycerol,
short chain fatty acids, and some
medium chain triglycerides can go directly into the circulatory system. Larger products,
such as the long chain fatty acids and monoglycerides must be formed into micelles,
absorbed into intestinal cells, incorporated into chylomicrons in the intestinal cell, and released into the lymph system. Once in the lymph system,
these chylomicrons (a class of lipoprotein) are released into the circulatory
system via the thorasic duct.
Chylomicrons circulate through the
body to deliver dietary fat to cells (with great efficiency!) and the liver. The liver
assembles lipoproteins made
up of triglycerides, cholesterol and proteins to form
Low Density Lipoprotein (LDLs) which deliver fat to cells, and High Density
Lipoproteins (HDLs) which carry fats from cells to the liver
Lipid Transport - HDLs (good
lipoproteins) and LDLs (bad lipoproteins) exist for the transportation of
fatty acids and cholesterol through the circulatory system. These lipoproteins deliver
building blocks (LDL) and clear excess materials (HDL) in the maintenance of cell
membranes and nervous tissue.
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Relative Sizes of Lipoproteins |
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